Thermo-lifting + Hydro-exfoliation

Zaffiro combines the power of thermo-lifting energy with an innovative microdroplet delivery system to infuse nano-encapsulated key ingredients evenly into the skin, resulting in deep hydration and uniform heating at the treatment site to tone and lift skin.

Key Features

Zaffiro brings together years of experience in scientific research and development, aesthetic medicine and engineering. The Zaffiro device has been sold worldwide since 2015 and has been carefully optimized to provide impressive results while maintaining high quality and safety standards.

delivery system

Microdroplet delivery system hydrates skin and improves lymphatic drainage.  


Biocompatible thermo-lift energy targets all three layers of the skin to significantly increase fibroblasts and stimulate long-term neocollagenesis


Sapphire glass ensures uniform heating and cooling for consistent results.



Thermo-lift energy is uniformly delivered to hydrated skin to increase fibroblasts by nearly 40% (after a single treatment), helping stimulate long-term neocollagenesis and angiogenesis to lift, tone and improve skin texture 1, 2.


No anesthetic required. Treatments can be performed in an hour or less with no lifestyle disruptions.


Complements other same-day combination therapies for increased practice revenue and patient satisfaction.

How It Works

The power of hydro-exfoliation and thermo-lift technology

Zaffiro works to enhance the appearance of skin by supporting healthy functions. Water peeling and exfoliation encourage a brightened complexion and skin cell proliferation. Thermo-lift technology encourages improved collagen health and long-term neocollagenesis providing firming and tightening to the appearance of the skin.


The thermo-lift, deep dermal heating technology works to shrink and thicken collagen fibers. Collagen remodeling can encourage tightening and lifting of the skin and improve firmness and elasticity. Improved collagen structure may help to improve the appearance of fine lines and wrinkles. Since deep dermal heating works to stimulate the skin’s healing and repair process, it encourages collagen health and neocollagenesis and provides long-term rejuvenation benefits.


The Zaffiro hydro-exfoliation treatment uses water peeling to deep clean, moisturize and improve skin texture. The treatment exfoliates and resurfaces the skin to noticeably improve skin texture and glow, while reducing the signs of aging.

The Science of Renewal

The thermo-lift, deep dermal heating technology delivers energy targeted in temperature and depth to improve existing collagen and stimulate neocollagenesis.


An in vivo clinical trial showed up to a 40% increase in fibroblasts 21 days after 1 Zaffiro treatment.*


Before Zaffiro treatment

21 days after 1 Zaffiro treatment

Before Zaffiro treatment

21 days after 1 Zaffiro treatment


In the same trial, a heightened level of CD31 indicated a lasting increase in angiogenesis 21 days post-treatment.

angio chart

Calderhead, R.G. and Tanaka, Y. (2017) Photobiological Basics and Clinical Indications of Phototherapy for Skin Rejuvenation. Photomedicine: Advances in Clinical Practice. May 17th 2017 DOI:10.5772/intechopen.68723

This diagram represents the structure of the skin in cross-section, including the epidermis, dermis and subcutaneous structures. Different areas of the face and body and different individuals will have varying depths and thickness of tissue layers.

Before & Afters

Zaffiro promotes and stimulates the natural functions of healthy skin. The water peeling and thermo-lift technologies provide both immediately noticeable and long-term benefits.



Have another question? Don’t hesitate to contact us directly.

Individual results will vary, but most patients see and feel improved lifting, tightening and firmness of the skin with improved texture and tone after each treatment.

Most patients will see immediate and long-time effects from their Zaffiro treatment. Results will continue to improve over the following months, as new collagen is formed.

The recommended number of treatments will vary depending on your specific concerns, expectations and severity of skin concern. Typically, we recommend a series of up to 4 treatments for the face or 6 treatments for the body with a maintenance treatment plan.

Zaffiro treatments are non-invasive and do not require any “downtime” for recovery. However, limiting exposure to the sun and daily application of SPF 50 is recommended.

Water peeling can be done as often as every week. Thermo-lifting is recommended monthly.


1 Mehta-Ambalal S. R. (2016). Neocollagenesis and Neoelastinogenesis: From the Laboratory to the Clinic. Journal of cutaneous and aesthetic surgery, 9(3), 145–151. doi:10.4103/0974-2077.191645

2 Sadick, N. (2008). Tissue Tightening Technologies: Fact or Fiction. Aesthetic Surgery Journal, Volume 28, Issue 2, March 2008, 180–188.

Get in Touch

Contact us to learn more about our aesthetic products.

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